Lytechinus pictus is found in the tropical and subtropical eastern Pacific Ocean at depths down to about 300 m (1,000 ft). Its range extends from central California southwards to Ecuador. In California it tends to inhabit the middle and lower intertidal zone but in the northern part of the Gulf of California it mainly inhabits the subtidal zone.
These sea urchins tend to form dense aggregations at the edge of, or inside, the kelp beds that line this coast. At San Onofre, California in 1978–79, the density of individuals close to the kelp beds was recorded at 80 per square metre while inside the kelp bed it was 40. At Anacapa Island, California, the highest densities (36 per sq.m.) were found in barren areas with coralline algae near the kelp beds.