The sixbar wrasse is diurnal and has a home range that exceeds 1,000 m2 (11,000 ft2). It forms small groups and feeds on planktonic and benthic crustaceans, foraminiferans, small fish, fish eggs and fish larvae. Males and females form pairs during the breeding season, and at this time males develop a gaudier colour and a black spot in the centre of the caudal fin.
An aquarium fish of this species was observed to use a rock as an anvil. The fish was fed pellets that were too hard for it to chew and too large for it to swallow. The fish carried each pellet to a particular rock where it succeeded in breaking the pellet into pieces. It used the same behaviour and the same rock on a number of occasions, demonstrating a capacity for remembering how to solve the hard-pellet problem.