C. quadricarinatus is native to permanent freshwater streams, billabongs and lakes on the north coast of the Northern Territory, northeastern Queensland, and Papua New Guinea. Through translocation by humans, the range has spread down to southern Queensland and into the far north of Western Australia, where it is outcompeting the local crayfish species . C. quadricarinatus is considered an invasive species, and has established feral populations in South Africa, Mexico, Jamaica, Puerto Rico, Indonesia, Zambia, Malaysia and Singapore.
This tropical crustacean is very tolerant of environmental changes, and is primarily a detritivore.