It is found from the easterly Balkan Peninsula to Spain and reaches its northerly limit in Great Britain, as well as Ireland (where it is considered introduced), where it is limited to some regions only: its highest densities are in chalk streams. A. pallipes is the only crayfish found in Ireland, occurring over limestone areas in rivers, streams, canals, and lakes. In France, A. pallipes is found in streams such as the Mornante and Sellon, two small tributaries of the Dorlay in the Loire department, where it is protected as a heritage species. It is also among the emblematic species of many French Natura 2000 sites as it tends to be less and less common in France while it used to be present in most rivers before North American crayfish species were introduced during the 20th century.
It has also been introduced to Corsica, Liechtenstein, and Portugal (from where it is now extirpated).